The Effect of Azalea on Oxidative Stress, Immune Factors and Vasodilator Factor in Hypertensive Rats

To analyze the effects of azalea on oxidative stress, immune factors and vasodilator in hypertensive rats. 24 male Specific-pathogen-free grade spontaneous hypertension rats were divided into model group (normal saline), (50 mg/kg/d azalea), verapamil verapamil) 8 normal control saline) observed changes tail artery systolic pressure for 2-18 w after administration, superoxide dismutase, malondialdehyde detected 18 The levels nuclear factor kappa B, Smooth muscle alpha-actin alpha actin by reverse transcription–polymerase chain reaction Western blot. caudal was significantly lower than that (p<0.05). Malondialdehyde reactive oxygen species Superoxide dismutase level higher interleukin-6 tumor necrosis factor-alpha those Angiotensin α endothelin-1 no nitric oxide synthase expression light enhancer activated B cells messenger Ribonucleic acid protein Azalea can reduce protect aortic injury. It may be related to reduction regulation diastolic factors, cells, expressions.